14 Oct 2016
As part of the 2016 Annual Review process for academic staff Alessio Ciulli, Vicky Cowling, Sonia Rocha and Helen Walden have been promoted to Personal Chair (Professor) and Sarah Coulthurst has been promoted to Reader. “I would like to congratulate these outstanding individuals for their well deserved promotions,” said Professor Julian Blow, Dean of Research in the School of Life Sciences. “Encouraging excellence is a core value of the School but that needs to be followed up with recognition and reward.
19 Aug 2016
Dr Sambit Nanda, a senior research scientist in the Medical Research Council’s Protein Phosphoryation and Ubiquitylation Unit (MRC-PPU) at the University of Dundee, has been awarded a research grant of £15,000 from Tenovus, Scotland to continue his exciting new research on inflammasomes.
17 Aug 2016
Scientists from the University of Dundee have discovered a key regulator of embryonic stem cell identity, research that could one day lead to new treatments for heart attack patients and those with congenital heart conditions. Embryonic stem cells have the potential to provide tissue replacement therapies for a number of debilitating diseases due to their capacity to differentiate into any cell type in the adult body, a property known as pluripotency.
09 Aug 2016
Mitochondria are the essential energy-generating powerhouses that provide our cells with the energy of life. However, their malfunction has a dark side. Damaged mitochondria have the potential to release destructive reactive oxygen species that have serious and deleterious consequences for the cell. To cope with this, our cells have evolved a protective mechanism to prevent such a “mitochondrial meltdown”, by eliminating damaged mitochondria through a process termed mitophagy.
01 Aug 2016
Researchers led by the University of Dundee’s Professor Dario Alessi have developed a new method of measuring the activity of disease-causing mutations in the LRRK2 gene, a major cause of inherited Parkinson’s disease. The team believes this research, which is published in Biochemical Journal, could help pave the way for future development of a clinical test that could facilitate evaluation of drugs to target this form of the condition.
01 Jul 2016
Researchers in the laboratory of Dr. Satpal Virdee have published the first example of genetically encodable aminooxy functionality, which can be installed site-selectively into recombinant proteins using genetic code expansion technology. The findings were published in Chembiochem this week.
30 Jun 2016
Satpal Virdee has been awarded a BBSRC Responsive Mode award of £650,000 allowing his lab to further develop technology they pioneered that enables the activity-based profiling of E3 ligases.
30 Jun 2016
Francesca Carrieri and Maithili Shroff to join Europe’s finest University students in creative and intellectual collaboration at Roche Continents 2016 Two Ph.D. students from Life Sciences at the University of Dundee have been invited to the highly prestigious Roche Continents - a full week of interdisciplinary challenges and inspiration at Roche Continents which takes place in Salzburg (during the Salzburg Festival) from 10th – 16th August 2016.
10 Jun 2016
In ground-breaking new work published in Molecular Cell, Yogesh Kulathu and colleagues report the discovery of a completely new family of Deubiquitinating enzymes (DUBs). Ubiquitin signals impact a wide range of eukaryotic biology. It is therefore very important that these signals are tightly regulated. This layer of regulation is provided by dedicated proteases called deubiquitinating enzymes (DUBs), of which there are ~100 encoded in the human genome that can be classified into five families.
07 Mar 2016
Pioneering chemical technology developed at the University of Dundee is giving scientists the clearest insight yet into crucial biochemical processes that are active in many diseases, including Parkinson’s disease. Dr Satpal Virdee, leader of the research team, said their findings could `revolutionise’ research capability. Already the Dundee team have used their newly developed tools to make new discoveries relating to the activity of the Parkin enzyme, which when mutated is a cause of Parkinson’s disease.