University of Dundee

all News

June 2018

May 2018

  • Francisco Bustos and Anna Segarra-Fas
    10 May 2018

    New research by Greg Findlay’s group in the MRC-PPU has made progress in understanding the fundamentals of intellectual disability, a developmental disorder thought to affect 1-2% of the world’s population. The paper by Francisco Bustos, a post-doctoral investigator, and Anna Segarra-Fas, a PhD student in Greg’s lab, shows that genetic mutations found in intellectual disability patients impair the catalytic activity of an E3 ubiquitin ligase called RNF12.

  • Professor Sir Phillip Cohen
    10 May 2018

    Following his recent Senior Investigator Award of £2.3million from the Wellcome Trust, Philip Cohen has now been awarde

  • Dario Alessi being presented with the Langston Award by Shalini Padmanabhan, Terina Martinez and Marco Baptista
    07 May 2018

    The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded MRC PPU Director Dario Alessi the 2018 MJFF Langston Award for “service and dedication to our shared goals of advancing Parkinson's understanding and therapeutic development”. For further information see here. 

April 2018

  • Satpal Virdee and Kuan-Chuan Pao
    12 Apr 2018

    Dr Virdee and colleagues in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) have discovered a novel class of E3 ligase. The E3 ligase, MYCBP2, operates in a unique way, selectively transferring ubiquitin to non-lysine amino acids with selectivity for threonine. The ubiquitin is linked to the threonine amino acid via a chemically distinct ester linkage thereby uncovering an unanticipated area of cellular biology. The findings are published in Nature.

  • Professor Dario Alessi
    12 Apr 2018

    Professor Sir Ian Wilmut – who led the team that created Dolly the sheep – has backed an initiative to tackle Parkinson’s disease, after being diagnosed with the condition.

  • Dominka Kwasna and Syed Arif Abdul Rehman
    04 Apr 2018

    In a paper just published in Molecular Cell, Dominka Kwasna from Yogesh Kulathu’s group at the MRC PPU, in collaboration with Ian Gibbs-Seymour at the University of Oxford, reports the discovery of a completely new class of enzymes that is important for protecting the cell’s DNA from damage.

March 2018

  • Gopal Sapkota
    23 Mar 2018

    Researchers from the University of Dundee and the Francis Crick Institute have made a significant discovery about a cellular pathway associated with developmental defects and a myriad of diseases ranging from alopecia to colorectal cancer.

  • Anna Segarra Fas, Stuart MacGowan and Jin-Feng Zhao
    19 Mar 2018

    Last week, the School’s Annual Research Symposium was held at Crieff Hydro. The programme of talks and poster presentations covered the diverse research taking place in the School. Newly appointed Principal Investigators and Professors gave talks alongside more junior members of the School, who spoke as part of the SLS showcase sessions.

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