18 Sep 2017
Life Sciences researcher Professor Karim Labib has been awarded £2million to explore the role that one of the most fundamental processes in cell biology plays in cancer. Professor Labib will receive the grant from Cancer Research UK to study mechanisms that preserve genome integrity during the final stages of chromosome replication in animal cells.
18 Jul 2017
Dr Miratul Muqit has been awarded the prestigious Francis Crick Medal and Lecture by the Royal Society in recognition of discoveries that have led to better understanding of the causes of Parkinson’s disease.
03 Jul 2017
Research by Rosalia Fernandez-Alonso, a post-doctoral investigator in Dr. Greg Findlay’s lab in the MRC-PPU, has been published in and featured on the cover of the July edition of the journal EMBO Reports. The paper identifies a new type of molecular switch involving BET bromodomain proteins, which enables embryonic stem (ES) cells to differentiate into mesendoderm, an important precursor cell that gives rise to tissues and organs such as pancreas, liver, heart and blood.
27 Jun 2017
Dr Miratul Muqit has received a prestigious award recognising his breakthroughs in understanding Parkinson’s disease. Dr Muqit is both a Consultant Neurologist at Ninewells Hospital, where he treats Parkinson’s patients, and a researcher carrying out cutting-edge research into the debilitating condition in the School. He has been awarded the 2018 Graham Bull Prize in Clinical Science and Goulstonian Lecture of the Royal College of Physicians (RCP).
23 Jun 2017
About five years ago, researchers in Philip Cohen’s lab discovered that a family of protein kinases, termed the Salt-Inducible Kinases (SIKs), keep macrophages in the pro-inflammatory state needed to combat infection, and that compounds suppressing SIK activity switch macrophages to an anti-inflammatory state that is critical for the resolution of inflammation.
14 Jun 2017
MRC PPU PI Mahima Swamy has been awarded a Sir Henry Dale Fellowship of £1.2 million to study the responses of the gut immune system to infection.
12 Jun 2017
Yogesh Kulathu from the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) has been awarded a 2017 Lister Research Prize. This prestigious and highly sought-after prize is given annually by the Lister Institute of Preventive Medicine to up to five young researchers in the UK. These awards are intended to help support and nurture future leaders of biomedical research.
02 Jun 2017
The protein TRAF6 is essential for the operation of many physiological processes, ranging from the development of sweat glands and the formation of bone to the operation of the innate immune system. TRAF6 is an E3 ubiquitin ligase and, for many years, it has been widely accepted that it is this enzymatic activity that mediates the essential functions of the protein.
12 May 2017
Scientists in the School have solved a mystery concerning one of the most fundamental processes in cell biology, in a new discovery that they hope may help to tackle cancer one day.
10 May 2017
University of Dundee researchers have shown that it is possible to rapidly target and destroy specific proteins in cells, raising the possibility of developing new ways of targeting ‘undruggable’ proteins in diseases.