Latest News for 05/2018
02 May 2018
At the Wellcome Centre for Anti-Infectives Research, we have made an exciting discovery about a group of life-threatening parasites.
15 Feb 2017
The Royal Society of Edinburgh has announced today that two academics from the School have been elected Fellows of Scotland’s national academy. The new Fellows are: ·David Horn, Professor of Parasite Molecular Biology ·John Rouse, Professor of Chromosome Biology “I am delighted to see our staff recognised among the range of new Fellows announced by the Royal Society of Edinburgh,” said Professor Sir Pete Downes, Principal and Vice-Chancellor of the University of Dundee.
27 May 2016
A genetic game of `winner takes all’ that sustains the parasitic infections which cause sleeping sickness in humans and nagana in cattle – devastating diseases particularly in rural areas of Africa - has been identified in a research breakthrough led by the University of Dundee. African trypanosomiasis, or sleeping sickness, affects both humans and animals and has a destructive impact, particularly in rural areas. The disease in humans is typically lethal without therapy and in cattle is the most economically important livestock disease in Africa.
22 Feb 2016
Professor David Horn, of the School of Life Sciences at the University of Dundee, is to be awarded the prestigious C.A. Wright Memorial Medal from the British Society for Parasitology.
05 Aug 2015
A mechanism that is responsible for the drug susceptibility of parasites that cause devastating diseases, known as nagana in cattle and sleeping sickness in humans, has been identified for the first time in a research breakthrough led by the University of Dundee. African trypanosomiasis is an infection affecting both animals and humans. It can have a devastating impact, particularly in rural areas, and is the most economically important livestock disease in Africa, where it is known as `nagana’.
29 Nov 2013
Researchers from David Horn's lab working with colleagues at the University of Sussex, have made a breakthrough in our understanding of how enzymes that make DNA, complete genome replication. Scientists studied a pair of primase polymerase-like (PPL) enzymes in the African trypanosome, a protozoan parasite that causes important diseases of humans and animals. These enzymes are also found in mammalian cells and many other eukaryotes.
26 Nov 2013
Scientists at the Universities of Dundee and Glasgow have discovered how drugs that have been used for 60 years to kill the parasite that causes sleeping sickness actually work. Research has revealed that the drugs used to attack Trypanosoma brucei enter through pores in the parasite’s cells known as aquaporins which function as water channels. It is the first time that drugs have been shown to enter cells through aquaporins and this may have major implications for drug delivery in other diseases.