Latest News for 06/2022
05 Jul 2021
Seven new papers have been published this month in The Biochemical Journal, representing a major collaboration between multiple groups at the Francis Crick Institute in London, University College London and The University of Dundee. Led by John Diffley at the Francis Crick Institute, with important contributions in Dundee from the groups of Yogesh Kulathu and Karim Labib in the MRC Protein Phosphorylation and Ubiquitylation Unit, together with Vicky Cowling in the division of Gene Regulation and Expression, the idea was to ‘repurpose’ existing drugs to combat the SARS-CoV-2 virus that caus
10 May 2018
New research by Greg Findlay’s group in the MRC-PPU has made progress in understanding the fundamentals of intellectual disability, a developmental disorder thought to affect 1-2% of the world’s population. The paper by Francisco Bustos, a post-doctoral investigator, and Anna Segarra-Fas, a PhD student in Greg’s lab, shows that genetic mutations found in intellectual disability patients impair the catalytic activity of an E3 ubiquitin ligase called RNF12.
29 Sep 2017
A new article from the Lamond group, published in eLife, reports the identification of the plant biflavone, hinokiflavone, as a pre-mRNA splicing modulator (Pawellek et al., 2017). In collaboration with Ron Hay’s group in GRE and the group of Richard Hartley, (University of Glasgow), they show that both natural and synthetic hinokiflavone inhibits splicing in vitro by blocking spliceosome assembly, specifically preventing progression from the spliceosome complex A to complex B.
30 Oct 2012
Congratulations to Katie Hands (Supervisor: Ron Hay) for successfully defending her PhD Thesis entitled 'Defining the mechanism of arsenic-induced degradation of PML'. Her internal examiner was Stephen Keyse of Ninewells and external examiner was David Grimwade, University of London.
10 Sep 2012
A paper published in the September 2012 issue of Nature reveals, for the first time, how enzymes stimulate the transfer of ubiquitin, the protein that plays a critical role in the proper functioning of cells and therefore in the development of disease. Professor Ron Hay of the Division of Gene Regulation and Expression at the College of Life Sciences, University of Dundee and Professor Jim Naismith of the University of St.
10 Sep 2012
Biochemical Society Novartis Award Lecture
25 Aug 2011
A collaboration between the labs of Angus Lamond, Anton Gartner, and Ron Hay at the Wellcome Trust Centre for Gene Regulation and Expression and Sarah Coulthurst of the Division of Molecular Microbiology at CLS, has established a quantitative proteomics technique in the nematode C.
23 Mar 2011
Congratulations to Ron Hay, the recipient of the 2012 Novartis Medal and Prize. This is the third consecutive year that the Novartis Prize has been awarded to a CLS scientist and the second consecutive year it has been won by PIs at the Wellcome Trust Centre for Gene Regulation and Expression. Angus Lamond was the recipient of the prize for 2011. Previous winners of the Prize from the College of Life Sciences also include and Grahame Hardie in 2010 and Sir Philip Cohen who gave the Novartis Medal Lecture in Warwick in 1992.
28 Feb 2011
Congratulations to Professor Ron Hay, the recipient of the 2012 Novartis Medal and Prize. This is the third consecutive year that the Novartis Prize has been awarded to a CLS scientist; Angus Lamond was the recipient of the prize for 2011 and Grahame Hardie in 2010. Previous winners of the Prize from the College of Life Sciences also include Sir Philip Cohen who gave the Novartis Medal Lecture in Warwick in 1992.
21 May 2010
Two Professors in the College of Life Sciences at the University of Dundee have been elected Fellows of the Royal Society, the world's oldest scientific academy in continuous existence. Professors Ron Hay and Angus Lamond have been elected Fellows in recognition of their contribution to our understanding of cellular structures and functions. Theirs is a rare double election for the College and means the College of Life Sciences at Dundee is now home to nine Fellows of the Royal Society, one of the strongest concentrations of Fellows in the UK.