Latest News for 08/2019
17 Apr 2019
Researchers from the Division of Cell Signalling and Immunology in the School have shown that a drug previously used to treat Type 2 diabetes could potentially be used to protect against cancer. A study carried out by Professors Grahame Hardie and Doreen Cantrell has shown that the drug phenformin protects mice against a type of cancer called T-cell lymphoma. It does this by switching on the protein AMPK, which was first defined by Professor Hardie in the 1980s. Subsequent research at Dundee showed a link between AMPK and cancer.
22 Nov 2017
Professor Doreen Cantrell, Wellcome Trust Principal Research Fellow at the School of Life Sciences, gave the Novartis Medal and Prize Lecture today at Charles Darwin House, London, UK. Seen as one of the UK’s most prestigious honours in biochemistry, the prize is awarded annually in recognition of contributions to the development of any branch of biochemistry and is open to candidates of any nationality working in the UK and Ireland. Professor was the 2017 recipient.
08 Jun 2017
Former Dundee researcher, Dr David Finlay, publishes recent findings in leading international journal Nature Communications. The work involved input from Dr Linda Sinclair from Professor Doreen Cantrell’s laboratory in the School who have a continuing collaboration with the Finlay group. Glucose – commonly referred to as a ‘simple’ sugar – may be a crucial factor in the fight against cancer and inflammatory disease after scientists discovered a new role for glucose in the stimulation of cells that work on the front line in the fight against infection and tumours.
09 May 2017
The Phenomics Discovery Initiative (PDi), a unique collaboration between the pharmaceutical industry and academia, has unveiled its first series of novel phenotypic assays. The assays are under development within the labs of the National Phenotypic Screening Centre (NPSC) – a collaboration between the Universities of Dundee, Edinburgh and Oxford - and are designed to identify new molecules with pharmacological activity in respiratory, oncology, immunology and c
19 Apr 2017
School of Life Sciences scientists have won a hat-trick of funding awards from the Wellcome Trust that will see more than £6million invested in their research. Professors Doreen Cantrell, Mark Field and Grahame Hardie have been successful in winning grants from Wellcome.
04 Nov 2016
Scientists at the University of Dundee have identified a `molecular commando’ which can be stealthily deployed to activate a hypoxic response, a process which can help to fight a range of conditions including stroke, angina, colitis and brain injuries. A Dundee team led by Professor Alessio Ciulli have used pioneering techniques to develop a `small molecule’ chemical probe called VH298, which offers highly targeted access to the parts of the cell which regulate hypoxia, known as the hypoxic signalling pathway.
27 Oct 2016
The world renowned biomedical research which takes place at the University of Dundee has received a multi-million pound boost from Wellcome, the global charitable foundation. Wellcome has awarded the University £3.75million from their Institutional Strategic Support Fund (ISSF), which enables universities in the UK and Ireland to invest in areas that are of mutual strategic importance to Wellcome and the individual institutions. The ISSF grant will support biomedical research at Dundee, in particular helping fund:
25 Apr 2016
Researchers at the University of Dundee have made new discoveries about the importance of nutrients for a subpopulation of white blood cells - T cells - that play a vital role in fighting cancer and infections. Professor Doreen Cantrell, Wellcome Trust Principal Research Fellow in the School of Life Sciences at the University, said the discovery opened up a new area to explore for pharmacological targets in T cell-mediated diseases, as well as in cancer therapy and chronic infection.
30 Mar 2016
Professor Doreen Cantrell, Wellcome Trust Principal Research Fellow and Dean of the School of Life Sciences at the University of Dundee, is to be awarded one of the UK’s most prestigious honours in biochemistry, the Novartis Medal and Prize.
How do killers kill? Cantrell and Lamond Lab collaboration sheds new light on body’s infection and...10 Nov 2015
Researchers at the University of Dundee have shed new light on the operations of a population of our white bloods cells which play a vital role in killing infected or tumorous cells and fighting infection and diseases like cancer. Cytotoxic T cells are a type of white blood cell found in the human body. They are known to be a strong part of our cellular defences but exactly how they work is not fully understood.