University of Dundee

Latest News for 11/2018

November 2018

  • “Allertek” team Luke Fulcher, Lambert Montava Garriga, Maria Zachari and Marianna Longo
    06 Nov 2018

    PhD students from the MRC PPU took part in the Biotechnology YES 2018 entrepreneurial competition last week. Luke Fulcher (Sapkota lab), Lambert Montava Garriga (Ganley lab), Maria Zachari (Ganley lab) and Marianna Longo (Ganley lab) formed the team “AllerTek” which sought to combat the presence of food allergens in meals.  The biotechnology YES competition allows PhD students from across the UK to compete against each other with their ideas in a “dragons den” style pitch to secure theoretical funding for their innovation.

March 2018

July 2017

  • 03 Jul 2017

    Research by Rosalia Fernandez-Alonso, a post-doctoral investigator in Dr. Greg Findlay’s lab in the MRC-PPU, has been published in and featured on the cover of the July edition of the journal EMBO Reports. The paper identifies a new type of molecular switch involving BET bromodomain proteins, which enables embryonic stem (ES) cells to differentiate into mesendoderm, an important precursor cell that gives rise to tissues and organs such as pancreas, liver, heart and blood.

May 2017

November 2013

October 2013

  • Lina Herhaus
    01 Oct 2013

    The TGFβ signalling pathway controls plethora of cellular functions during embryogenesis and in adult tissues. Consequently abnormal TGFβ signalling is associated with multiple human diseases such as fibrosis, immune disorders and cancer. TGFβ signalling is initiated upon ligand binding to a pair of receptor serine/threonine protein kinases on the cell surface. This triggers the phosphorylation of SMAD2/3 leading to the assembly and nuclear translocation of active SMAD2/3/4 transcriptional complex, which, together with other co-factors, drives the transcription of hundreds of target genes.