University of Dundee

Latest News for 01/2019

July 2018

November 2017

  • Journal of Cell Science Cover
    15 Nov 2017

    Maintenance of tissues requires a delicate balance between a number of processes such as the increase in the number of cells (proliferation) and the type of cells they become (differentiation).  Changes in this balance can lead to tumour formation.  Work from Professor Inke Näthke and her colleagues in the Division of Cell and Developmental Biology focussing on the intestinal tract and on colon cancer has shed further light on this area. 

March 2017

  • HerStory of Science
    10 Mar 2017

    HerStory of Science opened at the School of Life Sciences at the University of Dundee on Friday, 3rd March with some of the descendants of those featured in attendance. A series of outdoor posters consider the early history of women's contributions to science from a local perspective.

July 2016

  • 15 Jul 2016

    Altered tissue structure is a feature of many disease states and is usually measured by microscopic methods. This limits analysis to small areas so that regions with early transformation are easily missed.  Means to rapidly and quantitatively measure the structure and organisation of large tissue areas would represent a major advance not just for research but also in the clinic.  The Näthke lab worked with Prof.

June 2016

  • 29 Jun 2016

    The intestinal tract undergoes many changes during development.  To accommodate the growing body, it has to elongate and widen.  This also serves to increase the surface area for nutrient absorption. The key process that facilitates intestinal tissue expansion is called crypt fission. Importantly, crypt fission is also involved in adenoma growth. Despite the importance of crypt fission, the mechanisms controlling it are poorly understood. Understanding how crypt fission is regulated in normal tissue can help us to determine how the process changes in cancer.

April 2016

  • 25 Apr 2016

    PHOQUS PhD student Valerie Bentivegna, based in the Nathke lab, has been chosen to take part in the 2016 Soapbox Science challenge in Edinburgh.  She will join 15 other female scientists from across Scotland who have been selected to take part in the event, which is being held on the 24th of July on the Galleries precinct (The Mound) in Edinburgh. Getting on her soapbox, Valerie will be talking about how she combines different disciplines, including physics, engineering and biology - to "feel", "see" and "hear" the mechanical properties of colorectal cancer. 

  • 20 Apr 2016

    Work carried out in the Näthke lab, recently published in Molecular Biology of the Cell, has illustrated that proliferative fate and cell cycle duration in the intestine is set by the Wnt stimulus cells experience when they are ‘born’.  Using mathematical modeling together with high-resolution tissue imaging data, they also showed that the threshold for this response is lowered in transformed cells, before overt, histologically detectable tissue changes occur.

March 2016

October 2014

  • 16 Oct 2014

    One of our favourite Life Sciences images, Microtubules In Vitro by Ian Newton by Ian Newton and Paul Appleton of the Nathke Lab, has been shortlisted for the BBSRC's Images with Impact Competition.   You can view the image and votes for it at: http://bbsrc2014.picturk.com/, share the site and promote voting. The twitter hash tag is #ImageswithImpact.  

June 2013

  • 13 Jun 2013

    Researchers at the College of Life Sciences have been awarded a Wellcome Trust Grant to further build on the College’s success as an international centre of excellence in the fields of developmental and cell biology. The £800,000 multi-user equipment grant supports the purchase of a multi-photon laser-scanning microscope especially suited for development of cutting edge tissue imaging approaches.

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