University of Dundee

Latest News for 07/2022

November 2019

  • from left to right: Vladimir Borodkin, Andrii Gorelik, Daan van Aalten, Andrew Ferenbach, Sergio Galan Bartual
    07 Nov 2019

    A University of Dundee discovery has the potential to help scientists better understand neurological diseases such as Alzheimer’s and Parkinson’s. Researchers, led by Professor Daan van Aalten in the School, have developed a new way to tag proteins in human cells with a small sugar molecule called O-GlcNAc. There are over 20,000 proteins in every human cell and approximately 20% of these contain O-GlcNAc. The exact role played by O-GlcNAc remains a mystery but the molecule is found on proteins related to Alzheimer’s, Parkinson’s, motor neurone disease and intellectual disability.