Professor Marino Zerial from the Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany gave the Bridget Ogilvie Lecture 2017 today with a talk entitled "Mechanics in cell and tissue organization and function".
Marino Zerial graduated in biology at the University of Trieste in 1982 with a thesis on lysosomal storage disorders. He conducted post-doctoral experiences at the Institut J. Monod (Paris) on the organization of the human genome and at the European Molecular Biology Laboratory, EMBL (Heidelberg) on the biosynthesis and endocytosis of the tranferrin receptor. He became EMBL research Group Leader in 1991, when he started his work on the molecular regulation of endocytosis. In 1998, he became Max Planck Director and co-founder of the Max Planck Institute of Molecular Cell Biology and Genetics, MPI-CBG, Dresden. Marino Zerial has made key contributions towards the understanding of the molecular mechanisms of endocytosis. Particularly, his work on Rab5 as a master regulator of endosome biogenesis established key principles that are now textbook knowledge. In the past few years, Zerial’s group has performed a systems analysis of endocytosis using quantitative multi-parametric image analysis, revealing design principles of the endocytic network that are important for signalling. Zerial and colleagues have been developing methods for a multi-scale analysis of tissue organization and function, using the mouse liver as model system. For his scientific contributions, he was awarded the 1994 FEBS Anniversary Prize, the Chiara D’Onofrio Prize (1999), and the prestigious Gottfried Wilhelm Leibniz Prize (2006). Marino Zerial was elected EMBO Member in 1996 and is Honorary Professor at the Medical Faculty, University of Technology, Dresden.
The Bridget Ogilvie Lecture is named after Dame Bridget Ogilvie who was Director of the Wellcome Trust 1991 - 1998 and who played an important role in the development of the College (now School) of Life Sciences, in particular in the special award of £10 million that lead to the building of the Wellcome Trust Building in 1997. Each Wellcome funded Division in SLS takes turns in nominating the Bridget Ogilvie Lecturer and this year was the turn of BCDD.