The Peter Garland Lecture 2015
Professor James Rothman
Yale School of Medicine
“The regulation of neurotransmitter release”
Wednesday 8th April 2015 at 4pm
Large Lecture Theatre, MSI
Hosts: Professor Julian Blow/Professor Mike Ferguson
About the speaker:
Professor James Edward Rothman, the Wallace Professor of the Biomedical Sciences at Yale University, is one of the world's most distinguished biochemists and cell biologists. He is renowned for discovering the molecular machinery responsible for transfer of materials among compartments within cells. In so doing, Professor Rothman provided a unified conceptual framework for understanding such diverse and important processes as the release of insulin into the blood, communication between nerve cells in the brain, and the entry of viruses to infect cells. Numerous kinds of tiny membrane-enveloped vesicles ferry packets of enclosed cargo. Each type of vesicle must somehow deliver its specialized cargo to the correct destination among the maze of distinct compartments that comprise the cytoplasm of a complex animal cell. The delivery process, termed membrane fusion, is fundamental for physiology and medicine, as pathology in this process can cause metabolic, neuropsychiatric and other diseases.
Professor Rothman is Chairman of the Yale School of Medicine’s Department of Cell Biology and is the Director and founder of the Nanobiology Institute at Yale. He is also a research professor at University College, London. Professor Rothman graduated from Yale College (1971) where he studied physics. He received his Ph.D. degree in biological chemistry from Harvard (1976) and was a student at Harvard Medical School from 1971 to 1973. From 1976 to 1978, he completed a fellowship in the Department of Biology at the Massachusetts Institute of Technology. From 1978 to 1988, he was a professor in the Department of Biochemistry at Stanford University. Professor Rothman was the E.R. Squibb Professor of Molecular Biology at Princeton University (1988-1991). He founded and chaired the Department of Cellular Biochemistry and Biophysics at Memorial Sloan-Kettering Cancer Center (1991-2004), where he held the Paul A. Marks Chair and served as Vice-Chairman of Sloan-Kettering. Prior to moving to Yale in 2008, Professor Rothman was the Wu Professor of Chemical Biology in the Department of Physiology and Cellular Biophysics, and Director of Columbia University’s Sulzberger Genome Center.
Professor Rothman has received numerous awards and honors in recognition of his work, including the King Faisal International Prize for Science (1996), the Gairdner Foundation International Award (1996), the Lounsbery Award of the National Academy of Sciences (1997), the Heineken Foundation Prize of the Netherlands Academy of Sciences (2000), the Louisa Gross Horwitz prize of Columbia University (2002), the Lasker Basic Science Award (2002), the Kavli Prize for Neuroscience (2010), and the Nobel prize for Physiology or Medicine (2013). He is a member of the National Academy of Sciences (1993) and its Institute of Medicine (1995), and a Fellow of the American Academy of Arts and Sciences (1994).
About the lecture series:
The Peter Garland Lecture is the College of Life Sciences' most prestigious lecture. Peter Garland was the first Professor of Biochemistry in Dundee and under his leadership from 1970-1984 it became the UK’s strongest life sciences department.
The lecture will be followed by a wine reception in the LifeSpace gallery to which you are all cordially invited.