21 Jul 2014
Researchers from the University of Dundee have defined the structure of a recently discovered enzyme, raising the possibility of learning more about the evolution of organisms over billions of years. Using X-ray crystallography, Professor David Lilley and a team from the Cancer Research UK Nucleic Acid Structure Research Group at Dundee’s College of Life Sciences were able to determine the three-dimensional structure and mechanism of action of the ‘twister’ ribozyme, discovered by scientists at the University of Yale earlier this year.
18 Jul 2014
The spreading of a cancerous tumour from one part of the body to another may occur through pure chance instead of key genetic mutations, a new study has shown. Physicists from the University of Dundee and Arizona State University have used a statistical model to show that the formation of a new secondary tumour—commonly known as a metastasis—could just as likely derive from “common” cancer cells that circulate in the bloodstream, as from “specialist” cancer cells.
16 Jul 2014
A University of Dundee researcher has been awarded a £1.3million grant to boost research into the workings of the immune system. The Wellcome Trust Senior Investigator Award to Professor Paul Crocker will support his laboratory’s research for the next five years. Professor Crocker’s work focuses on proteins which regulate critical functions in our immune system and are influential in various infectious and autoimmune diseases and in septic shock.
10 Jul 2014
The College of Life Sciences is delighted to announce the winner of the 2014 Tim Hunt Prize for Cell Biology: Raman Das (Storey Lab) has won this year’s prize for his contribution to the field of Neurobiology. Using advanced imaging Raman has discovered a fundamentally new and unexpected form of cell sub-division, Apical abscission, which impacts cell differentiation.
10 Jul 2014
New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated. The discovery answers a key question about one of the most widely-researched proteins in human biology, which has been the subject of tens of thousands of research papers and millions of pounds in research funding.