University of Dundee

Only Connect: Satyajit Mayor’s visit to CLS (Monday 22 July 2013) to strengthen research links between Bangalore and Dundee

12 Jul 2013

Dr. Satyajit Mayor of the National Centre for Biological Sciences (NCBS) in India, will be visiting the College of Life Sciences on Monday 22 July 2013, to strengthen links between life sciences research in Dundee and the NCBS in Bangalore.

During his visit Dr. Mayor will visit the Drug Discovery Unit and the Proteomics facilities and meet a number of senior researchers at the College. He will also deliver two seminars , discussing the rapid growth of biological sciences research in Bangalore as well as his own research in cell biology.

Professor Mike Ferguson, Dean of Research at the College of Life Sciences said, “It makes perfect sense to strengthen and build on the existing links between our two institutions. Researchers at NCBS use experimental and computational approaches to the study of molecules, cells and organisms; and, like researchers here at CLS, they are aware that success in these fields requires collaboration between scientists from a variety of backgrounds in life sciences, physics, engineering, mathematics and computer science.

“I look forward to a very productive and mutually beneficial collaboration with Jitu Mayor and his colleagues at NCBS in Bangalore.”

Dr. Mayor’s talks will be held at 12:00 on Monday 22 July in the Small Lecture Theatre and will be hosted by Mike Ferguson.

'NCBS and its environs: The development and growth of a Biocluster in Bangalore'

'How cells regulate local membrane composition: the role of dynamic actin filaments in actively organising membrane domains'

From the speaker's website:

Only Connect: how cells tune-in via multiple mechanisms of endocytosis

No cell is an island: every second multitudes of atoms and molecules enter and exit. Thus does the cell breathe and converse, constantly sampling and responding to its environment. The rich flux of nutrients, signalling chemicals and ions indicates that the cell boundary is no sleepy frontier but a dynamic, highly-enabled transport facilitator. In fact, even just for ions and small molecules, inbound, the surrounding (plasma) membrane provides three possibilities: channels, carrier proteins and diffusion. For large molecules, which are ushered in via pinched-off in-pocketings of the plasma membrane, the known variations of this process (endocytosis) are even more numerous, and further discoveries are certain. Our laboratory is committed to exploring all facets of intake by endocytosis, exploiting new fluorescence microscopy techniques to directly visualize the in vivo nano-structure and activity of endocytic components. Our starting point is understanding the physico-chemical nature of the plasma membrane itself, and with Prof. Madan Rao we are pursuing our finding that the patches (or rafts) that concentrate molecules such as lipids and proteins in the membrane are much smaller than previously thought. Next, we are fleshing out the molecular basis of a novel mode of endocytosis in which these rafts are used but in which, uniquely to date, membrane in-pocketings are pinched off as vesicles without recourse to the girdling protein dynamin. The crucial significance of endocytic intake, cellular eavesdropping, for the whole organism is also being examined, in the model genetic system, Drosophila, with Prof. KS Krishnan and in the human immune system, with Dr S Rath.