Publications
Recent publications
Das, R.M. and Storey, K.G. (2012) Mitotic spindle orientation can direct cell fate and bias Notch activity in chick neural tube. EMBO Reports (in press), doi:10.1038/embor.2012.42
Das, R.M., Wilcock, A.C., Swedlow, J.R., and Storey, K.G. (2012) High-resolution live imaging of cell behaviour in the developing neuroepithelium. J. Vis. Exp. (Not Set), e3920, DOI: 10.3791/3920
Vilas-Boas, F., Fior, R., Swedlow, J.R., Storey, K.G., and Henrique, D. (2011) A novel Reporter of Notch Signalling indicates regulated and random Notch Activation during Vertebrate Neurogenesis. BMC Biology 9:58
Martínez-Morales P.L., Diez del Corral R., Olivera-Martínez, I., Quiroga, A.C., Das, R.M., Barbas, J.A., Storey, K.G., and Morales A.V. (2011) FGF and RA activity gradients control the timing of neural crest cell emigration in the trunk. J Cell Biol. 194(3), 489-503.
Bouskila, M., Esoof, N., Gay, L., Fang, E.H., Deak, M., Begley, M., Cantley, L.C., Prescott, A., Storey, K.G., Alessi, D.R. (2011) TTBK2 substrate specificity and the impact of spinocerebellar ataxia-causing mutations on kinase activity, localisation and development. Biochem. J. 437, 157-67.
Shiau, C.E., Das , R.M., and Storey, K.G. (2011) An effective assay for high cellular resolution time-lapse imaging of neurogenic placode formation and morphogenesis BMC Neuroscience, 12, 37.
Li, R and Storey, K.G. (2011) An emerging molecular mechanism for the neural vs mesodermal cell fate decision. Cell Research, 21(5), 708-710.
Stavridis, M.P., Collins, B.J. and Storey, K.G. (2010) Retinoic acid orchestrates Fibroblast growth factor signalling to drive embryonic stem cell differentiation. Development 137, 881-890.
Fishwick, K.J., Li, R.A., Deng, P. Halley, P. and Storey, K.G. (2010) Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube Developmental Biology 338, 215-225.
Wilson, V., Olivera-Martinez, I. and Storey, K.G. (2009). Stem cells, signals and vertebrate body axis extension. Development 136, 1591-1604.
Ekerot, M., Stavridis, M.P., Delavaine, L, Mitchell, M.P., Staples, C., Owens, D.M., Keenan, I.D., Dickinson, R.J., Storey, K.G. and Keyse, S.M. (2008) Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter. Biochem J. 2, 287-98.
Stavridis, M. S., Lunn, J.S., Collins, B.J. and Storey K.G. (2007) A discrete period of FGF/Erk1/2 activity is required for neural specification in embryos and ES cells. Development 134, 2889-94.
Olivera-Martinez I.M., and Storey, K.G. (2007) Wnt signals provide a molecular mechanism to control the timing of the FGF/Retinoid differentiation switch. Development 134, 2125-35.
Wilcock, A.C., Swedlow, J.R. and Storey, K.G. (2007) Mitotic spindle orientation distinguishes stem and terminal modes of neuron production in the early spinal cord. Development 134, 1943-54.
Lunn JS, Fishwick KJ, Halley PA, Storey KG. (2007) A spatial and temporal map of FGF/Erk1/2 activity and response repertoires in the early chick embryo. Developmental Biology 302, 536-52.
Smith TG, Karlsson M, Lunn JS, Eblaghie MC, Keenan ID, Farrell ER, Tickle C, Storey KG, Keyse SM (2006) Negative feedback predominates over cross-regulation to control ERK MAPK activity in response to FGF signalling in embryos. FEBS Lett. 580, 4242-5.
Das, R.M., Van Hateren, N.J., Howell, G.R., Farrell, E.R., Bangs, F., Porteous, V.C., Manning, E.M., McGrew, M.J., Ohyama, K., Sacco, M.A., Halley, P.A., Sang, H.M., Storey, K.G., Placzek, M., Tickle, C., Nair, V.K. & Wilson, S.A. (2006) A robust system for RNA interference in the chicken using a modified microRNA operon Developmental Biology 294, 554-63.
Akai, J., Halley, P.A. and Storey, K.G. (2005) FGF dependent Notch signalling maintains the spinal cord stem zone. Genes & Development 19, 2877-87.
Collins, B.J., Deak, M.J., Murray-Tait, V., Storey, K.G. and Alessi, D.R. (2005) In vivo role of the phosphate pocket of PDK1 defined by knockin mutation. Journal Cell Science 118, 5023-34
Delfino-Machin, M., Lunn, J.S., Breitkreuz, D.N., Akai, J. and Storey, K.G. (2005) Specification and maintenance of the spinal cord stem zone. Development 132, 4273-83
Diez del Corral, R. and Storey, K.G. (2004) Opposing FGF and retinoid pathways: a signalling switch that controls differentiation and patterning onset in the extending vertebrate body axis (2004) Bioessays 8, 857-69.
Diez del Corral, R., Olivera-Martinez, I., Goriely, A., Gale, E., Maden, M., and Storey, K (2003) Opposing FGF and Retinoid pathways control ventral neural patterning, neuronal differentiation and segmentation during body axis extension. Neuron 40, 65-79
Eblaghie, M., Lunn, J.S., Dickinson, R., Munsterberg A.E., Sanz-Ezquerro, J-J., Farrell, E.R., Mathers, J., Keyse, S.M., Storey K. & Tickle, C. (2003) Negative feedback regulation of FGF signalling levels by Pyst1/MKP3 in chick embryos. Current Biology 13, 1009-1018
Akai, J. and Storey, K. (2003) Brain or brawn: how FGF signaling gives us both. Cell 115, 510-2.
Akai, J. and Storey, K. (2002) Expression of gamma-adducin is associated with regions of morphogenetic cell movement in the chick embryo. Mechanisms of Development 119, (S1) 191-196.
Diez-del Corral, R. Breitkreuz, N. D., and Storey, K.G. (2002) Onset of neuronal differentiation in the spinal cord is regulated by the paraxial mesoderm and requires attenuation of FGF signalling. Development 129, 1681-91
Storey, K.G. (2002). "Vertebrate Neurogenesis" In Molecular Basis of Patterning in Vertebrate Development: Frontiers in Molecular Biology. Ed. C. Tickle O.U.P. pp.