The Blow Lab:

CR-UK Chromosome Replication Research Group

Publications 1986 - 1990

Blow, J.J. and Laskey, R.A. (1986). Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell 47, 577-587 [abstract] [pdf]

Blow, J.J. (1987). DNA replication: many strands converge. Nature 326, 441-442. [abstract]

Blow, J.J. and Watson, J.V. (1987). Nuclei act as independent and integrated units of replication in a Xenopus cell-free system. EMBO J. 6, 1997-2002. [abstract] [pdf]

Blow, J.J. and Watson, J.V. (1987). A probe for nascent DNA in intact nuclei. Trends Genet. 3, 233.

Blow, J.J., Dilworth, S.M., Dingwall, C., Mills, A.D. and Laskey, R.A. (1987). Chromosome replication in cell-free systems from Xenopus eggs. Phil. Trans. R. Soc. Lond. B 317, 483-494. [abstract]

Sheehan, M.A., Mills, A.D., Sleeman, A.M., Laskey, R.A. and Blow, J.J. (1988). Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs. J. Cell Biol. 106, 1-12. [abstract] [pdf]

     Blow J.J. (1988). Eukaryotic DNA replication reconstituted outside the cell. Bioessays 8, 149-152. [abstract]

Blow J.J. and Laskey, R.A. (1988). A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature 332, 546-548. [abstract] [pdf]

Blow, J.J., Sheehan, M.A., Watson, J.V. and Laskey, R.A. (1988). Regulated DNA replication in cell-free extracts of Xenopus eggs. Cancer Cells 6: Eukaryotic DNA Replication (Kelly T. and B. Stillman, eds.; Cold Spring Harbor Laboratory, New York) pp 297-303.

Minshull, J., Pines, J., Standart, N., Stewart, L., Mackie, S., Colman, A., Blow, J. Wu, M., Ruderman, J.V. and Hunt, T. (1988). Protein synthesis, proteolysis, and the control of cell division in early embryos: do the synthesis and destruction of cyclin comprises the cytoplasmic oscillator? In "Current Communications in Molecular Biology: Cell Cycle Control in Eukaryotes" (D. Beach, C. Basilico and J. Newport, eds.; Cold Spring Harbor Laboratory, New York) pp 128-139.

Blow, J.J. (1989). DNA replication and its control. Curr. Opinion Cell Biol. 1, 263-267. [abstract]

Minshull, J., Blow, J.J. and Hunt, T. (1989). Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis. Cell 56, 947-956. [abstract] [pdf]

Blow, J.J. (1989). Eukaryotic DNA replication requires both alpha and delta DNA polymerases. Trends Genet. 5, 134-136. [abstract]

Mills, A.D., Blow, J.J., White, J.G., Amos, W.B., Wilcock, D. and Laskey, R.A. (1989). Replication occurs at discrete foci spaced throughout nuclei replicating in vitro. J. Cell Sci. 94, 471-477. [abstract] [pdf]

Laskey, R.A., Fairman, M.P. and Blow, J.J. (1989). S phase of the cell cycle. Science 246, 609-614. [abstract]

Blow, J.J. (1989). Mitosis comes apart. Trends Genet. 5, 166-167. [abstract]

Minshull, J., Pines, J., Golsteyn, R., Standart, N., Mackie, S., Colman, A., Blow, J., Ruderman, J., Wu, M. and Hunt, T. (1989). The role of cyclin synthesis, modification and destruction in the control of cell division. J. Cell Sci. suppl. 12, 77-97. [abstract]

Blow, J.J., Sheehan, M.A., Watson, J.V. and Laskey, R.A. (1989). Nuclear structure and the control of DNA replication in the Xenopus embryo. J. Cell Sci. suppl. 12, 183-195. [abstract]

Blow, J.J. and Sleeman, A.M. (1990). Replication of purified DNA in Xenopus egg extract is dependent on nuclear assembly. J. Cell Sci. 95, 383-391. [abstract] [pdf]

Blow, J.J. and Nurse, P. (1990). A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts. Cell 62, 855-862. [abstract] [pdf]

Allen, T.D., Goldberg, M.W. and Blow, J.J. (1990). The use of in lens field-emission scanning electron-microscopy for studies of the organization of interphase nuclear chromatin and nuclear-pore formation. Inst. Phys Conf. Ser. 98, 663-666.