The Blow Lab:

CR-UK Chromosome Replication Research Group

Gaganmeet Singh Chadha


Tel: (+44)-1382-385868

Fax: (+44)-1382-388072


Singh, G., Jayanarayan, K.G. and Dey, C.S. (2005). Novobiocin induces apoptosis-like cell death in topoisomerase II over-expressing arsenite resistant Leishmania donovani. Mol Biochem Parasitol 141:57-69.

Singh, G. and Dey, C.S. (2007). Induction of apoptotic cell death by pentamidine and doxorubicin through differential inhibition of topoisomerase II in arsenite-resistant L. donovani. Acta Tropic 103:172-185.

Verma, N.K., Singh, G. and Dey, C.S. (2007). Miltefosine induces apoptosis in arseniteresistant Leishmania donovani promastigotes through mitochondrial dysfunction. Exp Parasitol 116:1–13.

Chavan, H.D., Singh, G. and Dey, C.S. (2007). Confocal microscopic investigation of tubulin distribution and effect of paclitaxel on post-translationally modified tubulins in sodium arsenite resistant Leishmania donovani. Exp Parasitol 116:320-326.

Bodiwala, H.S., Singh, G., Singh, R., Dey, C.S., Sharma, S.S., Bhutani, K.K. and Singh, I.P. (2007). Antileishmanial amides and lignans from Piper cubeba and Piper retrofractum. J Natural Med 61:418-421.

Singh, G., Jayanarayan, K.G. and Dey, C.S. (2008). Arsenite resistance in leishmania and possible drug targets. Adv Exp Med Biol 625, 1-8.

Singh, G., Chavan, H.D. and Dey, C.S. (2008). Proteomic analysis of miltefosine resistant Leishmania donovani. Int J Antimicrob Agents 31, 584-586.

Singh, G., Thakur, M., Chakraborti, P.K. and Dey, C.S. (2009). Evidence for the presence of R250G mutation at the ATPase domain of topoisomerase II in an arsenite-resistant Leishmania donovani exhibiting a differential drug inhibition profile. Int J Antimicrob Agents 33, 80-5.

Chadha, G.S. and Blow, J.J. (2010). Histone acetylation by Hbo1 tightens replication licensing. Mol. Cell 37, 5-6.

Poh, W.T., Singh Chadha, G., Gillespie, P.J., Kaldis, P. and Blow, J.J. (2014). Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated Protein Phosphatase 1. Open Biology 4:13013

Singh Chadha, G. and Blow, J.J. (2016). Xenopus Mcm10 is a CDK-substrate required for replication fork stability. Cell Cycle, in press.