Publications 2007

Liao H, Zhao Y, Baty DU, McGrath JA, Mellerio JE and McLean WHI (2007).  A heterozygous frameshift mutation in the V1 domain of keratin 5 in a family with Dowling-Degos disease.  J Invest Dermatol 127: 298-300 [Epub ahead of print, Aug 17, 2006].  (Pub Med ID: 16917491)

Barker JN, Palmer CNA, Zhao Y, Liao H, Hull PR, Lee SP, Allen MH, Meggit SJ, Reynolds NJ, Trembath RC and McLean WHI (2007).  Null mutations in the filaggrin gene (FLG) determine major susceptibility to early onset atopic dermatitis which persists into adulthood.  J Invest Dermatol 127: 564-567 [Epub ahead of print, Sep 21, 2006].  (Pub Med ID: 16990802)

Nomura T, Sandilands A, Akiyama M, Liao H, Evans AT, Sakai K, Ota M, Sugiura H, Yamamoto K, Sato H, Palmer CNA, Smith FJDMcLean WHI, Shimizu H (2007).  Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis.  J Allergy Clin Immun 119: 434-440.  (Pub Med ID: 17291859)

Zhao Y, Terron-Kwiatkowski A, Liao H, Lee SP, Allen MH, Hull PR, Campbell LM, Trembath RC, Capon F, Griffiths CEM, Burden D, McManus R, Hughes R, Kirby B, Fitzgerald O, Kane D, Barker JNWN, Palmer CNA Irvine AD and McLean WHI (2007).  Filaggrin null alleles are not associated with psoriasis.  J Invest Dermatol 127: 1878-82 [Epub ahead of print, 5th April 2007].  (Pub Med ID: 17410197)

Sandilands A, Terron-Kwiatkowski A, Hull PR, O’Regan GM, Clayton TH, Watson RM, Carrick T, Evans AT, Liao H, Zhao Y, Campbell LE, Schmuth M, Gruber R, Janecke AR, Elias PM, van Steensel MAM, Nagtzaam I, van Geel M, Steijlen PM, Munro CS, Bradley DG, Palmer CNA, Smith FJDMcLean WHI* and Irvine AD* (2007).  Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema.  Nat Genet 39: 650-654 [Epub ahead of print, 8th April 2007].  (Pub Med ID: 17417636)

McLean WHI and Irvine AD (2007).  Disorders of keratinisation: both rare and common genetic diseases of skin and other epithelial tissues.  Ulster Med J 76: 72-82.  (Pub Med ID: 17476820)

Palmer CNA, Ismail T, Lee SP, Terron-Kwiatkowski A, Zhao Y, Liao H, Smith FJDMcLean WHI and Mukhopadhyay S (2007).  Filaggrin null mutations are associated with increased asthma severity in children and young adults.  J Allergy Clin Immun 120: 64-68 [Epub ahead of print, 24th May 2007].  (Pub Med ID: 17531295)

Liao H, Waters A, Goudie DR, Aitken DA, Graham G, Smith FJD, Lewis-Jones S and McLean WHI (2007).  Filaggrin mutations are a genetic modifying factor exacerbating X-linked ichthyosis. J Invest Dermatol 127: 2795-2798 [Epub ahead of print, 26th July 2007].  (Pub Med ID: 17657246)

Liao H, Sayers JM, Wilson NJ, Irvine AD, Mellerio JE, Baselga E, Bayliss SJ, Uliana V, Fimiani M, Lane EB, McLean WHI, Leachman SA and Smith FJD (2007).  A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita.  J Dermatol Sci 48: 199-205 [Epub ahead of print, 23rd August 2007].  (Pub Med ID: 17719747)