Publications 2016

Allen EHA, Courtney DG, Atkinson SD, Moore JE, Mairs L, Toftgaard Poulsen E, Schiroli D, Maurizi E, Cole C, Hickerson RP, James J, Murgatroyd H, Smith FJD, MacEwen C, Enghild JJ, Nesbit MA, Leslie Pedrioli DM, McLean WHI, Moore CBT (2016) Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy. Hum Mol Genet 25:1176-1191. [Epub ahead of print 11 Jan 2016] (PubMed ID: 26758872)

Courtney DG, Moore JE, Atkinson SD, Maurizi E, Allen EHA, Pedrioli DM, McLean WHI, Nesbit MA, Moore CBT (2015) CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting. Gene Ther 23:108-112 [Epub ahead of print 20 Aug 2015] (PubMed ID: 26289666)

Forbes D, Johnston L, Gardner J, MacCallum SF, Campbell LE, Dinkova-Kostova AT, McLean WHI, Ibbotson SH, Dawe RS, Brown SJ (2016) Filaggrin genotype does not determine the skin's threshold to UV-induced erythema. J Allergy Clin Immunol 137:1280-1282  [Epub ahead of print 29 Jan 2016] (PubMed ID:26830116)

Kelleher MM, Dunn-Galvin A, Gray C, Murray DM, Kiely M, Kenny L, McLean WHI, Irvine AD, Hourihane JO (2016) Skin barrier impairment at birth predicts food allergy at 2 years of age.  J Allergy Clin Immunol 137:1111-1116 [Epub ahead of print 25 Feb 2016] (PubMed ID: 26924469)

Leitch CS, Natafji E, Yu C, Abdul-Ghaffar S, Madarasingha N, Venables ZC, Chu R, Fitch PM, Muinonen-Martin AJ, Campbell LE, McLean WHI, Schwarze J, Howie SE, Weller RB (2016) Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells. J Allergy Clin Immunol [Epub ahead of print 27 Feb 2016] (PubMed ID: 26934939)

Perkin MR, Craven J, Logan K, Strachan D, Marrs T, Radulovic S, Campbell LE, MacCallum SF, McLean WHI, Lack G, Flohr C; Enquiring About Tolerance Study Team (2016) Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: A population-based cross-sectional study.  J Allergy Clin Immunol [Epub ahead of print 28 Apr 2016] (PMID: 27241890)

Wilson NJ, Cole C, Kroboth K, Hunter WN, Mann JA, McLean WHI, Kernland Lang K, Beltraminelli H, Sabroe RA, Tiffin N, Sobey GJ, Borradori L, Simpson E, Smith FJD (2016) Mutations in POGLUT1 in Galli-Galli/Dowling-Degos disease. Br J Dermatol. [Epub ahead of print 1 Aug 2016] (PMID: 27479915)

Sekiya A, Kono M, Tsujiuchi H, Kobayashi T, Nomura T, Kitakawa M, Suzuki N, Yamanaka K, Sueki H, McLean WHI, Shimizu H, Akiyama M (2016) Compound heterozygotes for filaggrin gene mutations do not always show severe atopic dermatitis. J Eur Acad Dermatol Venereol [Epub ahead of print Aug 13, 2016] (PMID: 27519469)

Kennedy EA, Connolly J, Hourihane JO, Fallon PG, McLean WHI, Murray D, Jo JH, Segre JA, Kong HH, Irvine AD (2016) Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year. J Allergy Clin Immunol. [Epub ahead of print Sep 5, 2016] (PMID: 27609659)

McLean WHI (2016) Filaggrin failure - from ichthyosis vulgaris to atopic eczema and beyond. Br J Dermatol. Suppl 2:4-7 (PMID: 27667308)