Publications

• Simpson, G.G., Laurie, R.E., Dijkwel, P.P., Quesada, V., Stockwell, P.A., Dean, C. and Macknight, R.C. (2010) Non-Canonical Translation Initiation of the Flowering Time and Alternative Polyadenylation Regulator, FCA. Plant Cell 22:3764-77
• Hornyik, C., Duc, C., Rataj K., Terzi, L.C. and Simpson, G.G. (2010) Alternative Polyadenylation of Antisense RNAs in Flowering Time Control. Biochem Soc Trans 38:1077-81
• Hornyik, C., Terzi, L.C. and Simpson, G.G. (2010) The Spen Family Protein FPA Controls Alternative Cleavage and Polyadenylation of RNA. Developmental Cell 18:203-213.
  • See Commentary Articles:
  • (i) Rosonina E. and Manley J.I. (2010) Alternative Polyadenylation Blooms Developmental Cell 18: 172-174
  • (ii) Faculty of 1000 Biology FFa:9
• Terzi, L.C. and Simpson, G.G. (2009) Arabidopsis RNA Immunoprecipitation. Plant J 59:163-168.
• Terzi, L.C. and Simpson, G.G. (2008). Regulation of flowering time by RNA processing. In: Reddy, A.S. and Golovkin, M (ed.). Nuclear Pre-mRNA Processing in Plants. Springer, 201-208.
• Simpson, G.G. (2006) A Scottish Spring: Regulated gene expression in the control of flowering time. The Biochemist 28: 25-28
• Quesada, V., Dean, C., Simpson, G.G. (2005) Post-transcriptional regulation of Arabidopsis flowering. International Journal of Developmental Biology 49: 773-780.
• Henderson, I.R., Liu, F-Q., O'Drea, S., Simpson, G.G. and Dean, C. (2005) An allelic series reveals essential roles for FY in plant development in addition to flowering-time control. Development 132: 3597-3607.
• • See Commentary Article in:
    RNA processor - not just flower power Development 132 e1602
• Simpson, G.G. (2005) NO flowering. Bioessays 27: 239-41
• Simpson, G.G. (2004) The Autonomous pathway: epigenetic and post-transcriptional gene regulation in Arabidopsis flowering time control. Curr Opin Plant Biol. 7 570-574.
• Simpson, G.G., Quesada, V., Henderson, I.R., Dijkwel, P.P., Macknight, R. Dean, C. (2004) RNA processing and Arabidopsis flowering control. Biochem Soc Trans 32: 565-566.
• Simpson, G.G. (2003) Evolution of flowering in response to day-length:flipping the CONSTANS switch. Bioessays 25: 829-832
• Quesada,V., Macknight, R., Dean, C. and Simpson, G.G. (2003) Autoregulation of FCA pre-mRNA processing controls Arabidopsis flowering time. EMBO J 22: 3142-3152.
• • See Commentary Articles:
    (i) Science STKE (2003) An autonomous flowering pathway with an autoregulator. Sci.STKE issue 188, pptw243, 24 June 2003.
    
  • (ii)Faculty of 1000 Biology FFa:10
• Simpson, G.G., Dijkwel, P.P., Quesada, V., Henderson, I. and Dean C. (2003) FY is a 3'-end-RNA-processing factor that interacts with FCA to control the floral transition. Cell: 113, 777-787
  • See Commentary Articles:
• • (i) MacDonald C.C., Wyatt McMahon, K. (2003) The flowers that bloom in the spring: RNA processing and seasonal flowering. Cell 113: 671-672
• • (ii) Amasino, R. (2003) Flowering time: a pathway that begins at the 3' end. Current Biology 13 R670-R672).
• • (iii) Jaffe, S. (2003) An alternative polyadenylation mechanism blossoms. The Scientist 17 Aug 25 2003.
• • (iv) Faculty of 1000 Biology FFa:8
• Hedden, P., Holdsworth, M.J., Simpson, G.G., Edwards, K.J. and Lenton, J.R. (2002) New frontiers in plant development: from genes to phenotype. Trends in Plant Science 7: 381-383
• Simpson, G.G. and Dean, C. (2002) Arabidopsis, the Rosetta stone of flowering time? Science 296: 285-289
• Macknight, R., Duroux, M., Laurie, R., Dijkwel, P., Simpson, G.G. and Dean C. (2002) Functional significance of the alternative transcript processing of the Arabidopsis floral promoter, FCA. Plant Cell 14: 877-888
• • See Commentary Articles:
    (i) Eckardt NA (2002) Alternative splicing and the control of flowering time. Plant Cell 14: 743-747
• • (iv) Faculty of 1000 Biology FFa:7
• Lambermon, M.H.L., Simpson, G.G.,* Wieczorek-Kirk, D.A., Hemmings-Mieszczak, M. and Filipowicz, W. (2000) UBP1, a novel hnRNP-like protein that functions at multiple steps of higher plant pre-mRNA maturation. EMBO J 19: 1638-1649.
• *equal first author
• Simpson, G.G. and Dean, C. (2000) Environmental-dependent acceleration of a developmental switch: the floral transition. Science STKE 18:pe1.
• Dean, C., Dijkwel, P., Duroux, M., Gendall, T., Hutchison, C., Johanson, U., Levy, Y., Lister, C., Macknight, R., Smart, B., Simpson, G.G., Sivadon, P., Torney, K. and West, J. (1999) Molecular analysis of flowering time and vernalization response in Arabidopsis. Flowering Newsletter Nov 99: 6-11.
• Simpson, G.G., Gendall, A.R. and Dean, C. (1999) When to switch to flowering. Ann Rev Cell & Dev Biol. 99: 519-550.
• Simpson, G.G. and Filipowicz, W. (1996) Splicing of precursors to messenger RNA in higher plants: mechanism, regulation and sub-nuclear organization of the spliceosomal machinery. Plant Mol Biol 32: 1-41.
• Simpson, G.G., Clark, G., Rothnie, H., Boelens, W., Van Venrooij, W. and Brown, J.W.S. (1995) Molecular characterisation of the spliceosomal proteins U1A and U2B" in higher plants. EMBO J. 14: 4540-4550.
• Beven, A., Simpson, G.G., Brown, J.W.S. and Shaw, P. (1995) The organization of spliceosomal components in the nuclei of higher plants. J.Cell Science 108:509-518.
• Simpson, G.G., Clark, G. and Brown, J.W.S. (1994) Isolation of a maize cDNA encoding a protein with extensive similarity to an inhibitor of protein kinase C and a cyanobacterial open reading frame. Biochim. Biophys. Acta 1222:306-8.
• Brown, J.W.S, Simpson, G.G., Clark, G., Lyon, J., Kumar, A. and Simpson, C.G. (1993) Detection of antisense transcripts in transgenic plants by RT-PCR. The Plant J 4: 883-885.
• Brown, J.W.S., Simpson, C.G., Simpson, G.G., Turnbull-Ross, A.D. and Clark, G. (1993) Plant pre-mRNA splicing and splicing components. Phil Trans. Roy. Soc. B. 342:217-224.
• Kulesza, H., Simpson, G.G., Waugh, R., Beggs, J.D. and Brown, J.W.S. (1993) Detection of a plant spliceosomal protein analogous to the yeast splicing component, PRP8. FEBS Letts. 318:4-6.
• Simpson, C.G., Simpson, G.G., Clark, G, G., Leader, D.J., Vaux, P., Waugh, R. and Brown, J.W.S. (1992) Proc Roy Soc Edin 99B: 31-50.
• Simpson, G.G., Vaux, P., Clark, G., Waugh, R., Beggs, J.D. and Brown, J.W.S. (1991) Evolutionary conservation of the spliceosomal protein U2B". Nucleic Acids Res. 19: 5213-5217.
• Rowell, P. and Simpson, G.G. (1990) The role of amino acids and thioredoxin in the regulation of cyanobacterial G6PDH. In: Ullrich, W.R., Rigano, C., Fuggi, A. and Apaarici, P.J. (eds) Inorganic Nitrogen in Plants and Microorganisms. Springer-Verlag, Berlin, pp137-144.