A significant milestone in the development of a potential new antimalarial medicine has been reached by scientists at the University of Dundee, in partnership with the Medicines for Malaria Venture (MMV).
A compound developed in the Drug Discovery Unit at Dundee has been selected by MMV, following a positive recommendation by MMV’s Expert Scientific Advisory Committee, to enter preclinical development.
A new form of cell sub-division that is key to the development of the nervous system has been identified by researchers at the College of Life Sciences.
Neurons are vital to the development of the nervous system and in some regions of our brains they are continually produced throughout our lives. They are `born’ in a particular place in the early nervous system and then have to migrate to the correct place to make functional neural structures. (Attached image shows two newborn neurons shedding their tip ends, or abscising)
Scientists at the College of Life Sciences at the University of Dundee have identified a protein that could be key in the fight against cancer.
Researchers at the College's Centre for Gene Regulation and Expression have demonstrated that cancer cells need a protein called Bod1 to grow and divide. When this protein is removed cancer cells lose control of cell division and die.
An international collaboration led by the College of Life Sciences at the University of Dundee has made a significant breakthrough in understanding the causes of peanut allergy.
Peanut allergy affects 1-2% of children in the UK and may result in a severe or life-threatening allergic reaction. The number of people affected by peanut allergy has increased dramatically over the past 20-30 years, but the causes of the disease are unknown.
Eris Duro, a PhD student in John Rouse’s team in the MRC Protein Phosphorylation Unit, has discovered a complex of two proteins in human cells, termed MMS22L and TONSL, that plays a vital role in repairing DNA breaks that arise during the process of DNA replication.
