University of Dundee

“Mitotic chromosome mechanics”

Event Date: 
Wednesday, December 1, 2021 - 11:00 to 12:00
Event Location: 
Event Speaker: 
Prof. Daniel Gerlich
Institute of Molecular Biotechnology Vienna, Austria
Event Type: 

Abstract: Chromosomes dynamically reorganize during the cell cycle to support distinct functions at different stages. During interphase, chromosomes fill the cell nucleus as a relatively decondensed mass to enable transcription, replication, and DNA repair, whereas during mitosis they form compact bodies so that precisely one genome copy can be transported to each daughter cell. I will present our latest studies on how DNA loop extrusion and chromatin phase transitions contribute to the assembly, material properties, and segregation of mitotic chromosomes.  



Meeting ID: 811 5379 2798 

Passcode: 732490