University of Dundee

‘Inositol Pyrophosphates at the Interface of Cell Signalling and Metabolic Homeostasis’

Event Date: 
Monday, November 12, 2018 - 13:00 to Tuesday, November 13, 2018 - 14:00
Event Location: 
CTIR Sir Kenneth and Lady Noreen Murray Seminar Room
Host: 
Professor Dario Alessi FRS FRSE
Event Speaker: 
Dr Stephen Shears
Institution: 
National Institute of Environmental Health Sciences, National Institutes of Health
Event Type: 
Seminar
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Stephen Shears is one of the world’s leading experts in inositol phosphate signal transduction. 
 
He has made major contributions to understanding how inositol phosphate molecules are regulated and function. 
 
More recently Stephen has focused on studying the roles of inositol pyrophosphate molecules termed IP7 and IP8. His data suggest that these  act at the intersection of cell signaling and a biological mechanism that controls metabolic homeostasis. 
 
Stephen will talk about the enzymes that are involved in generating and breaking down IP7 and IP8 and the signalling roles that these molecules play in regulating processed or relevance to understanding inflammation, diabetes, obesity and cancer.
 
This seminar will be an excellent opportunity to learn about an interesting signalling pathway that is not extensively work on in Dundee
 
For more information on Stephen’s research please see https://irp.nih.gov/pi/stephen-shears