University of Dundee

‘Towards unveiling the functional impact of differential splicing.’

Event Date: 
Monday, May 15, 2017 - 14:00 to 15:00
Event Location: 
MSI Small Lecture Theatre
Host: 
Professor Geoff Barton FRSB
Professor John Brown
Event Speaker: 
Professor Eduardo Eyras
Institution: 
ICREA - Universitat Pompeu Fabra
Event Type: 
Seminar
Share

All Welcome

Abstract 

 

Eduardo Eyras from Universitat Pompeu Fabra (Barcelona) focuses on the development of computational tools to study differential RNA processing in the context of disease and development. Differential RNA processing involves alternative splicing, which has been proposed to provide the largest potential for dynamic gene regulation and molecular diversity. However, the impact of alternative splicing in protein sequence and function remains elusive. He will describe various approaches to investigate differential RNA processing and splicing across multiple conditions, and the potential impact on protein sequence and gene function. His work estimates the extent of functional differential splicing and he will discuss the possible implications in cancer.

 

This seminar should be of interest to anyone in areas of gene expression, alternative splicing and RNA-seq data exploratory analysis.

Eduardo will be in the School on Monday afternoon (15th) and at Plant Sciences/JHI on Tuesday 16th. Anyone wishing to speak to Eduardo should contact Linda Cunningham (cb-admin@dundee.ac.uk) or Margo Petrie (plantsciences-admin@dundee.ac.uk).