University of Dundee

Programming and Perturbing Cell Signaling Networks

Event Date: 
Monday, September 25, 2017 - 13:00
Event Location: 
MSI Small Lecture Theatre
Professor Dario Alessi FRS FRSE
Event Speaker: 
Professor Wendell Lim
University of California
Event Type: 
Dundee Cell Signalling Lecture

24th Dundee Cell Signalling Lecture

Wendell Lim is Professor and Chair of the Department of Cellular and Molecular Pharmacology at the University of California San Francisco and an Investigator of the Howard Hughes Medical Institute.  He received his A.B. in Chemistry, summa cum laude from Harvard College, his Ph.D. in Biochemistry and Biophysics at the Massachusetts Institute of Technology, and completed his postdoctoral training at Yale University.  His research focuses on the design principles of molecular circuits that govern cell decision-making and responses.  His lab has made contributions in understanding the molecular machinery of cell signaling and how molecular modules have been used in evolution to build novel new behaviours.  Most recently he has been a pioneer in the field of synthetic biology, exploring how these design principles can be harnessed to engineer cells with customized therapeutic response programs.


Wendell is interested in the design principles of cell signaling circuits that allow cells to sense their environment, to process this information, and to make complex response decisions. He is using synthetic biology approaches to systematically reconstitute signaling networks in order to better understand their design logic and fitness tradeoffs. His lab are harnessing their increasing understanding to build cells with useful customized sensing-actuator functions, such as therapeutic immune cells that can recognize and treat cancer or other diseases.  


The Dundee Cell Signalling Lecture is the MRC-PPU’s most important annual seminar in the field of Protein Phosphorylation.