University of Dundee

The University of Dundee is one of the leading universities in Europe for research in Life Sciences. In the most recent UK-wide assessment of research quality in UK higher education institutions – REF2014 –Dundee was ranked the top University in Biological Sciences. More recent rankings widely recognized as indicators of scientific excellence place Dundee high in their rankings. The CWTS Leiden Ranking 2019 for Biomedical and Health Sciences Impact places Dundee is 1st in the UK and Europe, 5th in the World as judged by ‘citations-per-paper’, one of the most widely recognized metrics of scientific excellence. This year’s ‘The State of Innovation’ report by Clarivate Analytics ranks Dundee as the most influential scientific research institution in the world for pharmaceuticals for the period 2006-16. The School enjoys a reputation as one of the most dynamic international centres for molecular cell biology, with outstanding laboratory and technology facilities.

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MRC Protein Phosphorylation Unit 2012

Al-Salihi, M. A., Herhaus, L. and Sapkota, G. P. (2012) Regulation of the transforming growth factor beta pathway by reversible ubiquitylation. Open Biol. 2, 120082
doi. 10.1098/rsob.120082
Pubmed. 22724073

Appleyard, M. V., Murray, K. E., Coates, P. J., Wullschleger, S., Bray, S. E., Kernohan, N. M., Fleming, S., Alessi, D. R. and Thompson, A. M. (2012) Phenformin as prophylaxis and therapy in breast cancer xenografts. Br J Cancer. 106, 1117-1122
doi. 10.1038/bjc.2012.56
Pubmed. 22361631

Gene Regulation and Expression 2008

Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. and Ferreira, J. (2008) Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity. Cancer research. 68, 2409-2418
doi: 10.1158/0008-5472.CAN-07-2092

Gene Regulation and Expression 2009

Ahel, D., Horejsi, Z., Wiechens, N., Polo, S. E., Garcia-Wilson, E., Ahel, I., Flynn, H., Skehel, M., West, S. C., Jackson, S. P., Owen-Hughes, T. and Boulton, S. J. (2009) Poly(ADP-ribose)-Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1. Science. 325, 1240-1243

Ahmad, Y., Boisvert, F. M., Gregor, P., Cobley, A. and Lamond, A. I. (2009) NOPdb: Nucleolar Proteome Database-2008 update. Nucleic Acids Research. 37, D181-D184

Gene Regulation and Expression 2010

Awad, S., Ryan, D., Prochasson, P., Owen-Hughes, T. and Hassan, A. H. (2010) The Snf2 Homolog Fun30 Acts as a Homodimeric ATP-dependent Chromatin-remodeling Enzyme. Journal of Biological Chemistry, 285, 9477-9484.

Bailly, A. P., Freeman, A., Hall, J., Declais, A.-C., Alpi, A., Lilley, D. M. J., Ahmed, S. and Gartner, A. (2010) The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair. PLoS Genet, 6, e1001025.

Cell Signalling and Immunology 2011

Aalto, K., Autio, A., Kiss, E. A., Elima, K., Nymalm, Y., Veres, T. Z., Marttila-Ichihara, F., Elovaara, H., Saanijoki, T., Crocker, P. R., Maksimow, M., Bligt, E., Salminen, T. A., Salmi, M., Roivainen, A. and Jalkanen, S. (2011) Siglec-9 is a novel leukocyte ligand for vascular adhesion protein-1 and can be used in PET imaging of inflammation and cancer. Blood. 118, 3725-3733
doi. 10.1182/blood-2010-09-311076
Pubmed. 21821708

Cell Signalling and Immunology 2012

Aregger, M. and Cowling, V. H. (2012) E2F1-dependent methyl cap formation requires RNA pol II phosphorylation. Cell Cycle. 11, 2146-2148
doi. 10.4161/cc.20620
Pubmed. 22592528

Berglund, F. M., Weerasinghe, N. R., Davidson, L., Lim, J. C., Eickholt, B. J. and Leslie, N. R. (2012) Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110alpha/PIK3CA but not by HER2 or mutant AKT1. Oncogene
doi. 10.1038/onc.2012.459
Pubmed. 23085752

Cell and Developmental Biology Publications 2008

Yue,Q., Wagstaff , L., Yang,X., Weijer C.J., and Münsterberg, A. (2008) Wnt3a mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function. Development 135, 1029-37

Sweetman, D., Wagstaff, L., Cooper, O., Weijer, C., and Münsterberg A. (2008) The migration of paraxial and lateral plate mesoderm cells emerging from the late primitive streak is controlled by different Wnt signals. BMC Dev Biol 8, 63-78