University of Dundee

The University of Dundee is one of the leading universities in Europe for research in Life Sciences. In the most recent UK-wide assessment of research quality in UK higher education institutions – REF2014 –Dundee was ranked the top University in Biological Sciences. More recent rankings widely recognized as indicators of scientific excellence place Dundee high in their rankings. The CWTS Leiden Ranking 2019 for Biomedical and Health Sciences Impact places Dundee is 1st in the UK and Europe, 5th in the World as judged by ‘citations-per-paper’, one of the most widely recognized metrics of scientific excellence. This year’s ‘The State of Innovation’ report by Clarivate Analytics ranks Dundee as the most influential scientific research institution in the world for pharmaceuticals for the period 2006-16. The School enjoys a reputation as one of the most dynamic international centres for molecular cell biology, with outstanding laboratory and technology facilities.

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Plant Sciences 2010

Bos, J. I. B., Armstrong, M. R., Gilroy, E. M., Boevink, P. C., Hein, I., Taylor, R. M., Tian, Z. D., Engelhardt, S., Vetukuri, R. R., Harrower, B., Dixelius, C., Bryan, G., Sadanandom, A., Whisson, S. C., Kamoun, S. and Birch, P. R. J. (2010) Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1. Proceedings of the National Academy of Sciences of the United States of America, 107, 9909-9914.

Plant Sciences 2011

Boevink, P. C., Birch, P. R. and Whisson, S. C. (2011) Imaging fluorescently tagged Phytophthora effector proteins inside infected plant tissue. Methods Mol Biol, 712, 195-209. PMID: 21359810

Gilroy, E. M., Taylor, R. M., Hein, I., Boevink, P., Sadanandom, A. and Birch, P. R. (2011) CMPG1-dependent cell death follows perception of diverse pathogen elicitors at the host plasma membrane and is suppressed by Phytophthora infestans RXLR effector AVR3a. New Phytol, 190, 653-666. PMID: 21348873

Plant Sciences 2012

Birch, P. R. J., Bryan, G., Fenton, B., Gilroy, E. M., Hein, I., Jones, J., Taylor, M., Torrance, L. and Toth, I. K. (2012) Re-localisation of late blight resistance protein R3a to endosomal compartments is associated with effector recognition and required for the immune response. Food Security. 4, 477-508

Nucleic Acid Structure Group 2008

Lilley, D.M.J. (2008) DNA Junctions and their Interaction with Resolving Enzymes In Protein-Nucleic Acid Interactions: Structural Biology [Eds Rice, P.A. and Correll, C.C.] RSC publications, 129-149.

Déclais, A.C., and Lilley, D.M.J. (2008) New insight into the recognition of branched DNA structure by junction-resolving enzymes Curr. Opin. Struct. Biol. 18, 86-95.

Lilley, D.M.J. (2008) Four-way helical junctions in DNA molecules in Mathematics of DNA Structure, Function, and Interactions. IMA In press.

Nucleic Acid Structure Group 2011

Aranda-Orgilles, B., Rutschow, D., Zeller, R., Karagiannidis, A. I., Kohler, A., Chen, C., Wilson, T., Krause, S., Roepcke, S., Lilley, D., Schneider, R. and Schweiger, S. (2011) Protein Phosphatase 2A (PP2A)-specific Ubiquitin Ligase MID1 Is a Sequence-dependent Regulator of Translation Efficiency Controlling 3-Phosphoinositide-dependent Protein Kinase-1 (PDPK-1). The Journal of biological chemistry. 286, 39945-39957
doi. 10.1074/jbc.M111.224451
Pubmed. 21930711

Nucleic Acid Structure Group 2009

Araki, L., Morita, K., Yamaguchi, M., Zhao, Z. Y., Wilson, T. J., Lilley, D. M. J. and Harusawa, S. (2009) Synthesis of Novel C4-Linked C-2-Imidazole Ribonucleoside Phosphoramidite and Its Application to Probing the Catalytic Mechanism of a Ribozyme. Journal of Organic Chemistry. 74, 2350-2356

Lilley, D. M. J. (2009) Comparative gel electrophoresis analysis of helical junctions in RNA. Methods in Enzymology, Vol 469: Biophysical, Chemical, and Functional Probes of Rna Structure, Interactions and Folding, Pt B. 469, 143-157

Molecular Microbiology 2008

Karnchanatat, A., Petsom, A., Sangvanich, P., Piapukiew, J., Whalley, A.J.S., Reynolds, C.D., Gadd, G.M., and Sihanonth, P. (2008) A novel thermostable endoglucanase from the wood-decaying fungus Daldinia eschscholzii (Ehrenb.:Fr.) Rehm. Enzyme and Microbial Technology 42, 404–413.

Fomina, M., Charnock, J.M., Hillier, S., Alvarez, R., Francis Livens, F., and Gadd, G.M. (2008) Role of fungi in the biogeochemical fate of depleted uranium. Current Biology 18, R375-R377.

Molecular Microbiology 2009

Andrell, J., Hicks, M. G., Palmer, T., Carpenter, E. P., Iwata, S. and Maher, M. J. (2009) Crystal Structure of the Acid-Induced Arginine Decarboxylase from Escherichia coli: Reversible Decamer Assembly Controls Enzyme Activity. Biochemistry. 48, 3915-3927

Coulthurst, S. J. and Sargent, F. (2009) Chaperone-signal peptide interactions on the Tat protein transport pathway. Febs Journal. 276, 3-3

Molecular Microbiology 2010

Ahmed, R. Z., Gadd, G. M. and Ahmed, N. (2010) Isolation of two Kocuria species capable of growing on various polycyclic aromatic hydrocarbons. African Journal of Biotechnology, 9, 3611-3617.

Borodkin, V. S. and van Aalten, D. M. (2010) An efficient and versatile synthesis of GlcNAcstatins-potent and selective O-GlcNAcase inhibitors built on the tetrahydroimidazo[1,2-a]pyridine scaffold. Tetrahedron, 66, 7838-7849.

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